Getting Started with Upneeq®

Getting Started with Upneeq®

How Do I Apply Upneeq?

Apply Upneeq to your affected eye(s) in 2 easy steps

Step 1: Cut open foil wrapper and remove single-use vial

Step 2: Apply one drop of Upneeq in each affected eye as directed, once a day

  • Do not let the tip of the vial touch your eye or any other surface
  • Vials should not be re-used after opening and should be thrown away after applying drop(s)
  • If you wear contact lenses, remove them before applying Upneeq eyedrops
    • You may put them back in 15 minutes after applying Upneeq
  • If more than one topical ophthalmic drug is being used, the drugs should be administered at least 15 minutes between applications

Upneeq should only be used as directed

  • Upneeq is designed to only be applied as an eyedrop
  • Each vial contains enough Upneeq solution to allow for one drop in each affected eye
  • The solution should never be swallowed or ingested in any other way
  • Storage requirements: Upneeq should be stored at 68°F-77°F (20°C-25°C) and should be protected from excessive heat
  • Keep out of reach of children
  • For complete instructions on using Upneeq, please see the Instructions for Use section in the full Prescribing Information

844-RVL-EYES (844-785-3937)

How Do I Get Upneeq?

Upneeq is available to all patients for a consistent and uniform price. Treatment is a choice between you and your doctor. RVL Pharmacy does not accept payments from insurance providers, which helps bypass insurance restrictions.

Upneeq is available exclusively through RVL Pharmacy and our friendly and knowledgeable pharmacy staff will contact you to facilitate home delivery. If you have any questions, you can contact RVL Pharmacy at 844-RVL-EYES (844-785-3937).

Say goodbye to trips to the pharmacy. Upneeq will be delivered conveniently to your doorstep.

The cost of Upneeq only varies by quantity but is the same for everyone:

  • 30-day supply is $105

Elevate your expectations for what prescription access should be with Upneeq

RVL Pharmacy ships to patients everywhere in the U.S. except for the following states: AL, AR, CA, CT, HI, IA, IL, MA, MD, ME, NE, OK, SC, TX, WV, and the District of Columbia.

Our partner KnippeRx ships to the 16 states listed above.

RVL Pharmacy
2500 Main Street Extension, Suite 10
Sayreville, NJ 08872
Phone: 844-RVL-EYES (844-785-3937)
Fax: 844-567-3937
Hours of Operation: Monday-Friday, 8 am to 8 pm, Eastern Time

- Click here for the address and hours of operation for KnippeRx

1250 Patrol Rd
Charlestown, IN 47111
Phone: 877-354-0292
Fax: 833-626-0715
Hours of Operation: Monday-Friday, 8 am to 8 pm, Eastern Time

Have more questions about Upneeq? Check out our FAQ section!

Patient FAQs

Get to know Upneeq a little better. Here are some commonly asked questions from patients interested in Upneeq.

Once your eye doctor sends your prescription to RVL Pharmacy, you will receive a phone call from RVL Pharmacy Call Center 844-RVL-EYES(844-785-3937). And don't worry if you miss our call; just call us back at 844-RVL-EYES(844-785-3937).

You will be getting a phone call from RVL Pharmacy:


Please save our number in your phone so you recognize us when we call you shortly!

RVL Pharmacy will verify your information and process your credit card payment with you over the phone. Once your payment is processed, your Upneeq prescription will be shipped directly to your preferred address.

You should receive your prescription for Upneeq within 2 to 4 days after payment.

RVL Pharmacy does not accept payments from insurance providers. Upneeq is available directly to patients through a fully transparent pricing model outside of the insurance process. The cost of Upneeq only varies by quantity, but is the same for all patients. A 30-day supply is $105.

RVL Pharmacy does not accept payments from insurance providers. Upneeq is priced transparently and consistently for all patients.

Yes. You will be sent a tracking number when Upneeq has shipped from RVL Pharmacy or KnippeRx. If you have any questions, call 844-RVL EYES (844-785-3937).

Patient Resources

Here are some additional resources that you may find useful.

Patient Education Brochure

You can meet Upneeq through this downloadable brochure. Learn more about what Upneeq can do, and how it is applied as a once-daily treatment.

Interactive Eye Assessment

If your eyes are looking a little tired, use this quick interactive tool to assess your eyelid(s). Be sure to share your results with your eye doctor during your next visit.